Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3013927 | 0.90 | TP53 (0.33) | RXFP1ALDH1A1CES2TP53 | |
| Hydrochloric Acid SCHEMBL3002522 | 0.89 | TP53 (0.32) | GAARXFP1ALDH1A1TP53POLB | |
| Hydrochloric Acid SCHEMBL3006107 | 0.88 | GAA (0.36) | GAAGPBAR1ALDH1A1CES2MEN1 | |
| Hydrochloric Acid SCHEMBL2995958 | 0.86 | GAA (0.35) | GAAGPBAR1ALDH1A1CES2MEN1 | |
| Hydrochloric Acid SCHEMBL3005946 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2999936 | 0.85 | NPSR1 (0.34) | GAAGPBAR1ALDH1A1CES2MEN1 | |
| Hydrochloric Acid SCHEMBL3009835 | 0.85 | ALDH1A1 (0.37) | GAAGPBAR1ALDH1A1CES2MEN1 | |
| Hydrochloric Acid SCHEMBL3014103 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3000698 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL2999516 | 0.81 | MEN1 (0.34) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190941-A1 | TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER | MITSUI CHEMICALS, INC. | 2010-07-29 | — | — | US | disclosed |
| US-20090043057-A1 | Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | MITSUI CHEMICALS , INC. | 2009-02-12 | — | — | US | disclosed |
| EP-1900744-A1 | TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043057-A1 | Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | OR10J3, PYM1, CCNE2 | GAA 4612/4885GPBAR1 3842/4885RXFP1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.