Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.56 |
| ▸ | ACHE | P22303 | 10/20 | 0.56 |
| ▸ | BCHE | P06276 | 9/20 | 0.56 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723491 | 1.00 | APP (0.56) | APPACHEBCHETRIM58NPY1R | |
| SCHEMBL23723225 | 0.94 | TRIM58 (0.62) | APPACHEBCHETRIM58NPY1R | |
| SCHEMBL30621752 | 0.94 | TRIM58 (0.62) | APPACHEBCHETRIM58NPY1R | |
| SCHEMBL30125157 | 0.87 | APP (0.58) | APPACHEBCHENPY1RNPY5R | |
| SCHEMBL23723420 | 0.87 | APP (0.58) | APPACHEBCHENPY1RNPY5R | |
| SCHEMBL26646037 | 0.87 | APP (0.57) | APPACHEBCHENPY1RNPY5R | |
| SCHEMBL23723434 | 0.87 | ACHE (0.60) | APPACHEBCHETRIM58PDE5A | |
| SCHEMBL30125353 | 0.87 | ACHE (0.60) | APPACHEBCHETRIM58PDE5A | |
| SCHEMBL30125330 | 0.86 | ACHE (0.56) | APPACHEBCHENPY1RNPY5R | |
| SCHEMBL23723463 | 0.86 | ACHE (0.56) | APPACHEBCHENPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339866-A1 | Quinazoline compounds and the use thereof in the treatment of cancer | TroBio Therapeutics Pty Ltd (AU) | 2023-10-26 | — | — | US | disclosed |
| EP-4100395-A1 | QUINAZOLINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER | Trobio Therapeutics Pty Ltd (AU) | 2022-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339866-A1 | Quinazoline compounds and the use thereof in the treatment of cancer | NQO2, TP53, ABL1 | APP 4864/4885ACHE 1215/4885BCHE 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.