Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824758 | 0.92 | KDM5B (0.38) | KDM5BSMN1; SMN2ALDH1A1MAPTP2RX3 | |
| SCHEMBL30125575 | 0.86 | HDAC1 (0.52) | HDAC1HDAC2HDAC8HRASESR1 | |
| SCHEMBL23745100 | 0.86 | HDAC1 (0.56) | HDAC1HDAC2HDAC8HRASESR1 | |
| Hydrochloric Acid SCHEMBL8894664 | 0.85 | KDM4E (0.46) | HDAC1HDAC2HDAC8HRASESR1 | |
| SCHEMBL30125639 | 0.84 | HDAC1 (0.43) | HDAC1HDAC2HDAC8KDM5BSMN1; SMN2 | |
| SCHEMBL30125658 | 0.84 | NAMPT (0.40) | HDAC1HDAC2HDAC8KDM5BSMN1; SMN2 | |
| SCHEMBL23744918 | 0.84 | HDAC1 (0.42) | HDAC1HDAC2HDAC8KDM5BSMN1; SMN2 | |
| SCHEMBL30125666 | 0.83 | HDAC1 (0.37) | HDAC1HDAC2HDAC8KDM5BALDH1A1 | |
| Hydrochloric Acid SCHEMBL28984120 | 0.83 | HDAC1 (0.41) | HDAC1HDAC2HDAC8KDM5BSMN1; SMN2 | |
| SCHEMBL31180736 | 0.81 | HDAC1 (0.42) | HDAC1HDAC2HDAC8KDM5BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360105-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. | 2024-10-31 | — | — | US | disclosed |
| EP-4384506-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023014793-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360105-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | POLI, POLR2A, POLR2B | HDAC1 489/4885HDAC2 551/4885HDAC8 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.