Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074941 | 0.84 | PDE2A (0.33) | MPLPDE2AEPHX2SLC1A5 | |
| SCHEMBL9404019 | 0.82 | MPL (0.41) | MPLPDE2AEPHX2 | |
| SCHEMBL19485985 | 0.79 | ALDH1A1 (0.35) | PDE2ASLC1A5 | |
| SCHEMBL16798567 | 0.79 | PDE2A (0.30) | PDE2ASLC1A5 | |
| SCHEMBL28056270 | 0.79 | PDE2A (0.33) | PDE2AEPHX2SLC1A5 | |
| SCHEMBL10710521 | 0.79 | EPHX2 (0.37) | PDE2AEPHX2SLC1A5 | |
| SCHEMBL14743948 | 0.79 | MPL (0.42) | MPLSCN9A | |
| SCHEMBL24572815 | 0.76 | IDO1 (0.44) | — | |
| SCHEMBL30127212 | 0.76 | IDO1 (0.44) | — | |
| SCHEMBL34473075 | 0.74 | HTR2C (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |