Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074941 | 0.82 | PDE2A (0.33) | PDE2ASLC1A5EPHX2KMOGRIN2B | |
| SCHEMBL30127239 | 0.79 | MPL (0.36) | PDE2ASLC1A5EPHX2 | |
| SCHEMBL19485985 | 0.78 | ALDH1A1 (0.35) | PDE2ASLC1A5 | |
| SCHEMBL16798567 | 0.78 | PDE2A (0.30) | PDE2ASLC1A5 | |
| SCHEMBL10710521 | 0.77 | EPHX2 (0.37) | PDE2ASLC1A5EPHX2KMOGRIN2B | |
| SCHEMBL28056190 | 0.75 | IDO1 (0.44) | — | |
| SCHEMBL28056275 | 0.74 | GRIN2B (0.36) | PDE2ASLC1A5EPHX2ACLYKMO | |
| SCHEMBL28056195 | 0.73 | MPL (0.40) | GRIN2B | |
| SCHEMBL7937713 | 0.73 | MPL (0.40) | GRIN2B | |
| SCHEMBL5328165 | 0.72 | KMO (0.34) | EPHX2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |