Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000886 | 0.88 | NTSR1 (0.55) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL30128446 | 0.87 | CXCR4 (0.50) | CXCR4 | |
| SCHEMBL29611859 | 0.86 | NTSR1 (0.55) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL1690986 | 0.85 | NTSR1 (0.54) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL1690987 | 0.85 | NTSR1 (0.54) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL31232959 | 0.85 | NTSR2 (0.48) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL416858 | 0.83 | NTSR2 (0.49) | NTSR2NTSR1OPRM1OPRD1F2 | |
| SCHEMBL416859 | 0.83 | NTSR2 (0.49) | NTSR2NTSR1OPRM1OPRD1F2 | |
| SCHEMBL29695547 | 0.82 | OPRM1 (0.49) | BDKRB2NTSR2NTSR1OPRM1OPRD1 | |
| SCHEMBL29752529 | 0.82 | NTSR2 (0.51) | NTSR2NTSR1OPRM1OPRD1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023389-B2 | Compositions that target tumor-associated macrophages and methods of use therefor | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-07-02 | — | — | US | claimed |
| US-20240131201-A1 | COMPOSITIONS THAT TARGET TUMOR-ASSOCIATED MACROPHAGES AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute | 2024-04-25 | — | — | US | claimed |
| US-11571484-B2 | Compositions that target tumor-associated macrophages and methods of use therefor | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-02-07 | — | — | US | claimed |