Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128747 | 0.84 | MAPK1 (0.51) | KMT2ALMNAPOLBRAB9AMEN1 | |
| SCHEMBL30128811 | 0.84 | SMN1; SMN2 (0.51) | KMT2ALMNAPOLBRAB9AMEN1 | |
| SCHEMBL30128766 | 0.82 | MAPT (0.50) | KMT2ALMNAPOLBRAB9AMAPT | |
| SCHEMBL30128797 | 0.82 | POLB (0.48) | KMT2ALMNAPOLBRAB9AMEN1 | |
| SCHEMBL28389854 | 0.80 | SMN1; SMN2 (0.53) | LMNAPOLBRAB9ANPC1GAA | |
| SCHEMBL16220985 | 0.79 | GRK2 (0.59) | KMT2AMMP13SMN1; SMN2TP53 | |
| SCHEMBL5748829 | 0.78 | POLB (0.64) | KMT2APOLBMEN1GAASMN1; SMN2 | |
| SCHEMBL30128644 | 0.78 | TP53 (0.57) | KMT2ALMNAPOLBRAB9AMEN1 | |
| SCHEMBL16221270 | 0.78 | ROCK2 (0.60) | POLBMMP13SMN1; SMN2TP53 | |
| SCHEMBL16221177 | 0.74 | CHRM1 (0.49) | KMT2ARAB9ANPC1MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |