Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128797 | 0.85 | POLB (0.48) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL30128766 | 0.85 | MAPT (0.50) | SMN1; SMN2POLBLMNARAB9AMAPT | |
| SCHEMBL30128747 | 0.85 | MAPK1 (0.51) | SMN1; SMN2POLBLMNARAB9ACYP1A2 | |
| SCHEMBL30128569 | 0.84 | KMT2A (0.52) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL28389854 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL5748829 | 0.81 | POLB (0.64) | SMN1; SMN2POLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30128644 | 0.81 | TP53 (0.57) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL30128774 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL19049515 | 0.75 | LMNA (0.61) | SMN1; SMN2POLBLMNATP53RAB9A | |
| SCHEMBL30128546 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBLMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |