Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389854 | 0.79 | SMN1; SMN2 (0.53) | MAPK1HTTPOLBGRK2 | |
| SCHEMBL30110945 | 0.77 | POLB (0.44) | HSD17B13KDM4ETRPA1ALDH1A1HSD17B10 | |
| SCHEMBL30110935 | 0.77 | MAPT (0.43) | HSD17B13KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL30110965 | 0.77 | HSD17B13 (0.58) | HSD17B13KDM4EMAPK1HTTGRK2 | |
| SCHEMBL14161796 | 0.76 | CNR1 (0.45) | HSD17B13KDM4ETRPA1ALDH1A1HSD17B10 | |
| SCHEMBL30111001 | 0.76 | HSD17B10 (0.49) | HSD17B13KDM4EMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL30956620 | 0.76 | CNR1 (0.50) | HSD17B13KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL30111258 | 0.76 | HSD17B13 (0.63) | HSD17B13KDM4EMAPK1HTTHSD17B10 | |
| SCHEMBL30111117 | 0.75 | ALDH1A1 (0.52) | HSD17B13KDM4EHTTTRPA1ALDH1A1 | |
| SCHEMBL30128619 | 0.74 | GRK2 (0.52) | TRPA1PSMB2GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |