Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128824 | 0.90 | PDE5A (0.51) | GRK2PSMB2TRPA1MAPTSTAT1 | |
| SCHEMBL30129021 | 0.85 | GRK2 (0.49) | GRK2P2RX3 | |
| SCHEMBL30128680 | 0.85 | MCL1 (0.50) | GRK2P2RX3RAB9A | |
| SCHEMBL30128600 | 0.85 | TRPA1 (0.52) | GRK2P2RX3TRPA1KMT2A | |
| SCHEMBL30128609 | 0.85 | GRK2 (0.49) | GRK2P2RX3MMP13CASR | |
| SCHEMBL30128753 | 0.81 | P2RX3 (0.61) | P2RX3MAPT | |
| SCHEMBL28389854 | 0.81 | SMN1; SMN2 (0.53) | GRK2RAB9A | |
| SCHEMBL30128668 | 0.81 | L3MBTL1 (0.58) | GRK2P2RX3MAPTKMT2A | |
| SCHEMBL30553041 | 0.80 | MAPT (0.47) | TRPA1SCDMAPTMMP13STAT1 | |
| SCHEMBL24754381 | 0.76 | DDR1 (0.54) | GRK2TRPA1SCDMMP13STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |