Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314157 | 0.72 | MAPT (0.46) | POLBMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL20320311 | 0.71 | NTRK1 (0.56) | POLBL3MBTL1ALDH1A1HPGDNTRK1 | |
| SCHEMBL9510331 | 0.70 | POLB (0.61) | POLBMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4057059 | 0.69 | ELANE (0.70) | MAPTELANEKDM4EGAAKMT2A | |
| SCHEMBL597831 | 0.69 | MAPT (0.57) | MAPTL3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL31617087 | 0.69 | KMT2A (0.52) | POLBMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL3850358 | 0.68 | NTRK1 (0.55) | MAPTL3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL31617053 | 0.68 | KMT2A (0.51) | POLBMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL1877271 | 0.67 | SMN1; SMN2 (0.52) | POLBMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL11689824 | 0.66 | CYP1A2 (0.68) | POLBMAPTL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336704-B | Danshensu derivative and preparation method and medical application thereof | 上海大学 | 2022-10-11 | — | — | CN | disclosed |