Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510379 | 0.81 | KMT2A (0.52) | KMT2AHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL8511661 | 0.80 | KMT2A (0.60) | POLBKMT2AHPGDKDM4EMEN1 | |
| SCHEMBL31617087 | 0.80 | KMT2A (0.52) | POLBKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL28634605 | 0.77 | POLB (0.50) | POLBKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL31617053 | 0.76 | KMT2A (0.51) | POLBKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL28594274 | 0.75 | NTRK1 (0.56) | KMT2AHPGDALDH1A1GAANPC1 | |
| SCHEMBL7097815 | 0.74 | MAPT (0.41) | POLBKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11042738 | 0.73 | SMN1; SMN2 (0.49) | KMT2AHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL3429282 | 0.73 | FAAH (0.49) | KMT2AALDH1A1TP53LMNACHRNA7 | |
| SCHEMBL3387671 | 0.73 | POLB (0.69) | POLBKMT2AHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333131-B1 | Plant protective agent based on pyrazolecarboxylic acid derivatives | HOECHST AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| EP-0333131-A1 | Plant protective agent based on pyrazolecarboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-20 | — | — | EP | disclosed |