Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207290 | 0.87 | ADORA2B (0.32) | — | |
| Hydrochloric Acid SCHEMBL1805025 | 0.85 | ADORA2B (0.31) | — | |
| Bromide SCHEMBL2439099 | 0.85 | ADORA2B (0.31) | — | |
| Iodide SCHEMBL4566525 | 0.85 | ADORA2B (0.31) | — | |
| Fluoride SCHEMBL28263051 | 0.85 | ADORA2B (0.31) | — | |
| Water SCHEMBL28225074 | 0.85 | ADORA2B (0.31) | — | |
| Sulfurous Acid SCHEMBL17668120 | 0.84 | ADORA2B (0.31) | — | |
| Acetic Acid SCHEMBL14164759 | 0.83 | SMN1; SMN2 (0.34) | ALDH1A1RAB9A | |
| SCHEMBL16649431 | 0.82 | FDPS (0.34) | KMT2A | |
| SCHEMBL2575220 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005553-B1 | METHOD OF CHARGING LITHIUM SULFUR CELLS | SION POWER CORP (US) | 2014-12-03 | — | — | EP | claimed |
| EP-1726052-B1 | ELECTROLYTES FOR LITHIUM SULFUR CELLS | SION POWER CORP (US) | 2012-03-14 | — | — | EP | claimed |