Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.62 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392389 | 1.00 | MAOA (0.70) | MAOANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL6519242 | 0.91 | MAOA (0.70) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8657871 | 0.88 | ACSL1 (0.67) | MAOANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL5030900 | 0.88 | ACSL1 (0.70) | MAOANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL27895770 | 0.85 | ACSL1 (0.66) | MAOANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL12240937 | 0.85 | KDM4E (0.58) | MAOANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL20594363 | 0.85 | ACSL1 (0.72) | MAOAACSL1ACSL6XDHMAOB | |
| SCHEMBL20594290 | 0.85 | ACSL1 (0.72) | MAOAACSL1ACSL6XDHMAOB | |
| SCHEMBL20594368 | 0.85 | ACSL1 (0.72) | MAOAACSL1ACSL6XDHMAOB | |
| SCHEMBL20594883 | 0.85 | ACSL1 (0.72) | MAOAACSL1ACSL6XDHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611926-B | Non-sensitive bond bridged SN38 dimer prodrug, self-assembled nanoparticle thereof and application thereof | 沈阳药科大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115611926-A | Non-sensitive bond bridged SN38 dimer prodrug, self-assembled nanoparticles thereof and application | 沈阳药科大学 | 2023-01-17 | — | — | CN | disclosed |