Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240938 | 0.88 | CYP1A2 (0.55) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL392389 | 0.85 | MAOA (0.70) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30130333 | 0.85 | MAOA (0.70) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10895137 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL1798063 | 0.80 | NPC1 (0.57) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL12240985 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL12240936 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL15003206 | 0.79 | CYP1A2 (0.62) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10454060 | 0.79 | PARP10 (0.51) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL1798229 | 0.78 | ACSL1 (0.58) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741659-B2 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | OSAKA UNIVERSITY (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20120238029-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | RBM3, HNRNPA3, HNRNPAB | KDM4E 4335/4885ALDH1A1 1251/4885HPGD 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.