Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.44 |
| ▸ | HTR3B | O95264 | 5/20 | 0.44 |
| ▸ | HTR3A | P46098 | 5/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22085166 | 0.89 | PIK3CA (0.58) | PIK3CAMAP4K4HTR1AHTR2C | |
| SCHEMBL22085229 | 0.81 | L3MBTL1 (0.43) | PIK3CA | |
| SCHEMBL22085234 | 0.79 | PIK3CA (0.36) | PIK3CAMAP4K4 | |
| SCHEMBL4107521 | 0.76 | PTPN1 (0.44) | MAP4K4 | |
| SCHEMBL22085175 | 0.73 | ATR (0.47) | PIK3CA | |
| SCHEMBL20588645 | 0.73 | PIK3CA (0.43) | PIK3CAHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23889678 | 0.73 | TGFBR1 (0.35) | MAP4K4 | |
| SCHEMBL10292423 | 0.73 | PTPN1 (0.38) | — | |
| SCHEMBL10001044 | 0.73 | PTPN2 (0.34) | MAP4K4 | |
| SCHEMBL5080208 | 0.73 | MAP4K4 (0.47) | PIK3CAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028892-B | Application of 4-amino-pyrrolotriazine derivative in preparation of anti-pulmonary fibrosis preparation | 天津全和诚科技有限责任公司 | 2022-12-16 | — | — | CN | disclosed |