Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245063 | 0.88 | LMNA (0.55) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL28152802 | 0.86 | LMNA (0.53) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL9351447 | 0.85 | LMNA (0.45) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL18262815 | 0.82 | LMNA (0.53) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Alcohol SCHEMBL9765954 | 0.82 | ALOX15 (0.51) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL18262905 | 0.82 | LMNA (0.49) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL8975143 | 0.82 | LMNA (0.49) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL14981162 | 0.80 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL18262891 | 0.79 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL214157 | 0.78 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63303940-A | — | — | None | — | — | JP | disclosed |
| EP-2188272-B1 | PHENYL- AND BENZYLTHIAZOLYLPIPERAZINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | REMYND NV (BE) | 2016-02-24 | — | — | EP | disclosed |
| US-8877341-B2 | Polycarbonate resin and optical film using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8722681-B2 | N-sulfonyl thiazolylpiperazine derivatives and related N-sulfonyl heterocyclic derivatives for the treatment of neuro degenerative diseases | NV REMYND (BE) | 2014-05-13 | — | — | US | disclosed |
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | NV REMYND (BE) | 2010-08-05 | — | — | US | disclosed |
| US-20100196720-A1 | POLYCARBONATE RESIN AND OPTICAL FILM USING THE SAME | ABB TECHNOLOGY LTD. (CH) | 2010-08-05 | — | — | US | disclosed |
| EP-2053072-A1 | POLYCARBONATE RESIN AND OPTICAL FILM USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-04-29 | — | — | EP | disclosed |
| JP-S63303940-A | PRODUCTION OF BISPHENOLS | IDEMITSU KOSAN CO LTD | 1988-12-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | SMN1; SMN2, HTT, SNCA | LMNA 80/4885TRPA1 1011/4885CHRM1 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.