Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723612 | 1.00 | PIM1 (0.43) | PIM1PIM2CDC7CCNE1CDK2 | |
| SCHEMBL30132032 | 0.84 | CDC7 (0.41) | PIM1PIM2CDC7CCNE1CDK2 | |
| SCHEMBL23723615 | 0.84 | CDC7 (0.41) | PIM1PIM2CDC7CCNE1CDK2 | |
| SCHEMBL30120693 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ALPLKDM4EKMT2AALPI | |
| SCHEMBL26521621 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ALPLKDM4EKMT2AALPI | |
| SCHEMBL26521619 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ALPLKDM4EKMT2AALPI | |
| SCHEMBL30132092 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ALPLKDM4EKMT2AALPI | |
| SCHEMBL23723530 | 0.83 | PIM1 (0.42) | PIM1PIM2ALDH1A1ALPLKDM4E | |
| SCHEMBL30132088 | 0.83 | PIM1 (0.42) | PIM1PIM2ALDH1A1ALPLKDM4E | |
| SCHEMBL30120633 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALPLKDM4EKMT2AALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |