SCHEMBL30132035

SCHEMBL30132035

Oc1cc(O)c2ccc3c(O)cc(O)c4ccc1c2c43

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
ALOX15 P16050 3/20 0.41
HSD17B10 Q99714 3/20 0.41
APP P05067 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
THRB P10828 2/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
SNCA P37840 1/20 0.41
TRPM4 Q8TD43 1/20 0.38
PIM1 P11309 1/20 0.37
NQO2 P16083 1/20 0.36
IDO1 P14902 1/20 0.35
LMNA P02545 3/20 0.35
HTT P42858 2/20 0.35
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 4/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13736031 0.82 ALDH1A1 (0.52) MAPTALOX15HSD17B10APPHPGD
SCHEMBL29440260 0.82 ALDH1A1 (0.52) MAPTALOX15HSD17B10APPHPGD
SCHEMBL29104759 0.80 ALDH1A1 (0.50) MAPTALOX15HSD17B10APPHPGD
SCHEMBL5992452 0.78 APP (0.32) MAPTALOX15HSD17B10APPHPGD
SCHEMBL29440243 0.76 MPL (0.49) MAPTALOX15HSD17B10APPHPGD
SCHEMBL4957991 0.76 MPL (0.49) MAPTALOX15HSD17B10APPHPGD
SCHEMBL590946 0.75 MPL (0.47) MAPTALOX15HSD17B10APPHPGD
SCHEMBL16380316 0.75 MPL (0.33) HSD17B10LMNAALDH1A1CA12CA2
SCHEMBL15523070 0.75 MPL (0.47) MAPTALOX15HSD17B10APPHPGD
SCHEMBL1108351 0.74 TRPM4 (0.41) MAPTALOX15HSD17B10APPHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4132586-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY Tiba Biotech LLC (US) 2023-02-15 EP claimed
CN-115702005-A Vectors for efficient nucleic acid delivery 蒂巴生物技术有限公司 2023-02-14 CN claimed
EP-4132586-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY Tiba Biotech LLC (US) 2023-02-15 EP disclosed
CN-115702005-A Vectors for efficient nucleic acid delivery 蒂巴生物技术有限公司 2023-02-14 CN disclosed