Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 7/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723528 | 1.00 | PDE5A (0.40) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL23723538 | 0.90 | PDE5A (0.40) | PDE5AALDH1A1HTTRXFP1PIM1 | |
| SCHEMBL30132068 | 0.90 | PDE5A (0.40) | PDE5AALDH1A1HTTRXFP1PIM1 | |
| SCHEMBL23723691 | 0.88 | PDE5A (0.41) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL23723613 | 0.88 | PDE5A (0.37) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL30120668 | 0.84 | PIM1 (0.37) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL23723517 | 0.84 | PIM1 (0.37) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL30132075 | 0.81 | ALPL (0.41) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL23723556 | 0.81 | ALPL (0.41) | PDE5AALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL23723534 | 0.81 | TNKS (0.37) | PDE5AALDH1A1KDM4EHTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |