Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723538 | 1.00 | PDE5A (0.40) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723691 | 0.93 | PDE5A (0.41) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723617 | 0.90 | PDE5A (0.39) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723528 | 0.90 | PDE5A (0.40) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL30132101 | 0.90 | PDE5A (0.40) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723613 | 0.86 | PDE5A (0.37) | PDE5AHTTRXFP1ALDH1A1NPSR1 | |
| SCHEMBL30132102 | 0.82 | ALDH1A1 (0.43) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723507 | 0.82 | ALDH1A1 (0.43) | PDE5ATDP1HTTRXFP1ALDH1A1 | |
| SCHEMBL23723741 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1NPSR1POLBMAPK1 | |
| SCHEMBL30132084 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1NPSR1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |