Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21592410 | 0.88 | S1PR4 (0.47) | FSCN1POLBALDH1A1HTTRAB9A | |
| SCHEMBL2090466 | 0.83 | POLB (0.47) | FSCN1POLBALDH1A1HTTMEN1 | |
| SCHEMBL2090468 | 0.83 | POLB (0.47) | FSCN1POLBALDH1A1HTTKMT2A | |
| SCHEMBL12763813 | 0.81 | POLB (0.42) | POLBALDH1A1HTTMEN1LMNA | |
| SCHEMBL11616132 | 0.79 | RAB9A (0.48) | ALDH1A1HTTRAB9AMEN1LMNA | |
| SCHEMBL11616130 | 0.79 | RAB9A (0.48) | ALDH1A1HTTRAB9AMEN1LMNA | |
| SCHEMBL23723677 | 0.78 | HTT (0.44) | POLBALDH1A1HTTRAB9AMEN1 | |
| SCHEMBL17513418 | 0.78 | FSCN1 (0.53) | FSCN1POLBALDH1A1HTTRAB9A | |
| SCHEMBL10441682 | 0.77 | ALDH1A1 (0.40) | FSCN1ALDH1A1HTTLMNANOTUM | |
| SCHEMBL6393802 | 0.77 | FSCN1 (0.61) | FSCN1POLBALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |