Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554618 | 1.00 | PIK3CA (0.41) | PIK3CAMEN1KMT2AHTTNPC1 | |
| SCHEMBL20014212 | 0.83 | PIK3CA (0.56) | PIK3CAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL20554639 | 0.80 | PIK3CA (0.45) | PIK3CAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL20554833 | 0.79 | SHBG (0.55) | PIK3CAMEN1KMT2AHTTNPC1 | |
| SCHEMBL30132562 | 0.79 | SHBG (0.55) | PIK3CAMEN1KMT2AHTTNPC1 | |
| SCHEMBL20554676 | 0.79 | PIK3CA (0.40) | PIK3CAMEN1KMT2AHTTSHBG | |
| SCHEMBL9717586 | 0.78 | MAPK1 (0.40) | PIK3CAMEN1KMT2AHTTNPC1 | |
| SCHEMBL10768717 | 0.75 | CHRNA7 (0.46) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL20554784 | 0.75 | PIK3CA (0.37) | PIK3CAMEN1KMT2AHTTNPC1 | |
| SCHEMBL20554382 | 0.75 | MAPT (0.42) | PIK3CAMEN1KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| EP-4126835-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |