Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554668 | 1.00 | ALOX5AP (0.44) | ALOX5APFEN1LOXL2LOXIDO1 | |
| SCHEMBL27894825 | 0.82 | LOXL2 (0.50) | ALOX5APFEN1LOXL2LOXIDO1 | |
| SCHEMBL1643206 | 0.81 | ALDH1A1 (0.47) | ALOX5APFEN1LOXL2LOXKCNH2 | |
| SCHEMBL20554243 | 0.75 | SCN9A (0.52) | CA2KCNH2SCN5ASCN9AALDH1A1 | |
| SCHEMBL30132565 | 0.75 | TSHR (0.47) | ALDH1A1MAPT | |
| SCHEMBL20554364 | 0.75 | TSHR (0.47) | ALDH1A1MAPT | |
| SCHEMBL20554634 | 0.74 | TLR8 (0.40) | KCNH2SCN5ASCN9AALDH1A1MAPT | |
| SCHEMBL5669483 | 0.74 | BLM (0.48) | ALOX5APFEN1LOXL2LOXTGFBR1 | |
| SCHEMBL29564344 | 0.73 | SCN9A (0.53) | KCNH2SCN5ASCN9AALDH1A1MAPT | |
| SCHEMBL29564492 | 0.73 | KCNH2 (0.43) | KCNH2SCN5ASCN9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |