Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054514 | 1.00 | TP53 (0.40) | TP53TEAD1MTNR1ASCN9AKCNH2 | |
| SCHEMBL30132586 | 0.87 | TEAD1 (0.50) | TEAD1MTNR1ASCN9AKCNH2SCN5A | |
| SCHEMBL19054515 | 0.87 | TEAD1 (0.50) | TEAD1MTNR1ASCN9AKCNH2SCN5A | |
| SCHEMBL24088989 | 0.86 | MTNR1A (0.52) | TP53MTNR1ASCN9AKCNH2SCN5A | |
| SCHEMBL20554320 | 0.84 | TP53 (0.41) | TP53TEAD1MTNR1AKCNH2POLB | |
| SCHEMBL19054517 | 0.80 | TEAD1 (0.38) | TP53TEAD1MTNR1AKCNH2POLB | |
| SCHEMBL19054508 | 0.79 | TP53 (0.43) | TP53TEAD1MTNR1APOLBMAPT | |
| SCHEMBL30132600 | 0.79 | TP53 (0.43) | TP53TEAD1MTNR1APOLBMAPT | |
| SCHEMBL19054516 | 0.79 | MTNR1A (0.53) | TP53TEAD1MTNR1APOLBMAPT | |
| SCHEMBL22472832 | 0.74 | POLB (0.40) | TEAD1MTNR1APOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |