Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132640 | 0.86 | TP53 (0.40) | MTNR1AMTNR1BTP53POLBMAPT | |
| SCHEMBL19054514 | 0.86 | TP53 (0.40) | MTNR1AMTNR1BTP53POLBMAPT | |
| SCHEMBL9786948 | 0.82 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL20554767 | 0.76 | HTT (0.37) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL30132647 | 0.76 | HTT (0.37) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL19054515 | 0.73 | TEAD1 (0.50) | MTNR1ASCN9AKCNH2SCN5A | |
| SCHEMBL30132586 | 0.73 | TEAD1 (0.50) | MTNR1ASCN9AKCNH2SCN5A | |
| SCHEMBL20554826 | 0.72 | MTNR1A (0.48) | MTNR1AMTNR1BMAPT | |
| SCHEMBL4518453 | 0.72 | MTNR1A (0.48) | MTNR1AMTNR1BMAPT | |
| SCHEMBL6088362 | 0.72 | MTNR1A (0.71) | MTNR1ATP53POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332455-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20210380551-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380551-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | NR1H2, NR1H3, NCOA1 | MTNR1A 186/4885MTNR1B 372/4885TP53 3092/4885 |
| US-11332455-B2 | α,β-unsaturated amide compound | NR1H2, NCOA1, NR0B1 | MTNR1A 161/4885MTNR1B 371/4885TP53 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.