Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554390 | 1.00 | RAB9A (0.41) | RAB9AKDM4EALDH1A1POLBMAPK8 | |
| SCHEMBL19054525 | 0.87 | BRD4 (0.41) | KDM4EMAPK8CARM1PRMT6MAPK14 | |
| SCHEMBL20554778 | 0.84 | BRD4 (0.42) | RAB9AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL19054523 | 0.82 | KDM4E (0.47) | RAB9AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL30132677 | 0.82 | KDM4E (0.47) | RAB9AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL20554355 | 0.77 | RAB9A (0.45) | RAB9AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL30132681 | 0.77 | RAB9A (0.45) | RAB9AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL20554889 | 0.76 | L3MBTL1 (0.39) | KDM4EL3MBTL1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30132567 | 0.76 | L3MBTL1 (0.39) | KDM4EL3MBTL1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL20554733 | 0.76 | L3MBTL1 (0.42) | KDM4EL3MBTL1SMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |