Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431769 | 0.86 | CA12 (0.43) | AKT2AKT1ERN1NT5EROCK2 | |
| SCHEMBL15849790 | 0.83 | AKT2 (0.61) | AKT2AKT1ERN1ABL1PIM1 | |
| SCHEMBL29533228 | 0.83 | AKT2 (0.61) | AKT2AKT1ERN1ABL1PIM1 | |
| SCHEMBL20040983 | 0.82 | NPBWR1 (0.44) | AKT2AKT1ERN1NT5EROCK2 | |
| SCHEMBL23292140 | 0.81 | FDPS (0.47) | AKT2AKT1ERN1NT5EABL1 | |
| SCHEMBL29464728 | 0.81 | FDPS (0.47) | AKT2AKT1ERN1NT5EABL1 | |
| SCHEMBL3740850 | 0.80 | AKT2 (0.70) | AKT2AKT1ABL1PIM1PIM3 | |
| Hydrochloric Acid SCHEMBL32685369 | 0.79 | FDPS (0.46) | AKT2AKT1ERN1NT5EPIM1 | |
| SCHEMBL17980346 | 0.79 | NT5E (0.59) | AKT2AKT1NT5ECHEK1RPS6KA3 | |
| Hydrochloric Acid SCHEMBL23291955 | 0.79 | FDPS (0.46) | AKT2AKT1ERN1NT5EPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386511-B2 | METHODS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-03-20 | — | — | EP | claimed |
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |