Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133210 | 0.98 | HRH3 (0.52) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL6305023 | 0.93 | HRH3 (0.53) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| Bromide SCHEMBL2924741 | 0.92 | HRH3 (0.52) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL11268814 | 0.83 | HRH3 (0.53) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| Hydrochloric Acid SCHEMBL11272072 | 0.81 | HRH3 (0.52) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL5195380 | 0.81 | KMT2A (0.74) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL31010303 | 0.81 | KMT2A (0.74) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL1888525 | 0.80 | HRH3 (0.78) | HRH3ALDH1A1SMN1; SMN2POLBHRH4 | |
| Hydrochloric Acid SCHEMBL16825143 | 0.79 | KMT2A (0.72) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL31097161 | 0.79 | KMT2A (0.77) | HRH3CHKAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |