Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | CHKA | P35790 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | MC5R | P33032 | 1/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195380 | 0.98 | KMT2A (0.74) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL31010303 | 0.98 | KMT2A (0.74) | KMT2ACHKAHRH3ACHEPKM | |
| Hydrochloric Acid SCHEMBL16825143 | 0.96 | KMT2A (0.72) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL31392631 | 0.96 | CHKA (0.79) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL27999347 | 0.92 | KMT2A (0.89) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL8852275 | 0.90 | CHKA (0.67) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL4750742 | 0.87 | KMT2A (1.00) | KMT2ACHKAACHEPKMMC4R | |
| SCHEMBL13940581 | 0.87 | CHKA (0.76) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL10135595 | 0.85 | SLC6A4 (0.64) | KMT2ACHKAHRH3ACHEPKM | |
| SCHEMBL6377576 | 0.85 | KMT2A (0.72) | KMT2ACHKAHRH3ACHEPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350210-A | Preparation method of naphthalene derivative with nitrogen-containing heterocycle | 苏州爱玛特生物科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | LUNAC THERAPEUTICS LTD (GB) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294498-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F7 | KMT2A 3026/4885CHKA 2760/4885HRH3 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.