Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PAK4 | O96013 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26130603 | 1.00 | SYK (0.55) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24996518 | 0.81 | SYK (0.56) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL15233158 | 0.81 | SYK (0.56) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10266502 | 0.78 | SYK (0.52) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2588073 | 0.77 | NR4A2 (0.50) | CYP1A2CYP3A4CYP2C19TDP1NR4A2 | |
| SCHEMBL30168960 | 0.75 | HTR3A (0.50) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23861062 | 0.75 | HTR3A (0.50) | SYKCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21574347 | 0.75 | TYK2 (0.40) | SYKMAPK1NR4A2CLK4CDC7 | |
| SCHEMBL12526131 | 0.74 | YTHDC1 (0.37) | SYKLMNALRRK2 | |
| SCHEMBL31329846 | 0.74 | NR4A2 (0.56) | SYKCYP3A4HSD17B10NR4A2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |