Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 18/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 18/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 18/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 15/20 | 0.39 |
| ▸ | TSHR | P16473 | 14/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224726 | 0.85 | KDM4C (0.41) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL24849056 | 0.80 | MAPT (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL31236928 | 0.80 | MAPT (0.42) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL27224637 | 0.80 | KDM4C (0.46) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL31401688 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL26984959 | 0.74 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30746514 | 0.74 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30746419 | 0.74 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL26985343 | 0.74 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL23694527 | 0.73 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003014-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | 中外製薬株式会社 | 2023-01-26 | — | — | WO | disclosed |