Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.35 |
| ▸ | USP2 | O75604 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224637 | 0.86 | KDM4C (0.46) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30135702 | 0.85 | CYP1A2 (0.39) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL24849056 | 0.83 | MAPT (0.42) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31236928 | 0.83 | MAPT (0.42) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31401688 | 0.76 | CYP1A2 (0.44) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30746514 | 0.75 | CYP1A2 (0.40) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL26984959 | 0.75 | CYP1A2 (0.40) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29425460 | 0.72 | AURKA (0.46) | KDM4CMAPTKDR | |
| SCHEMBL27224639 | 0.72 | AURKA (0.46) | KDM4CMAPTKDR | |
| SCHEMBL38651248 | 0.72 | MAPT (0.44) | KDM4CMAPTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327355-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-10-03 | — | — | US | disclosed |
| EP-4375273-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327355-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | BRAF, RAF1, NRAS | KDM4C 273/4885MAPT 3820/4885CYP1A2 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.