Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 9/20 | 0.36 |
| ▸ | USP2 | O75604 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849056 | 1.00 | MAPT (0.42) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27224637 | 0.94 | KDM4C (0.46) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24849057 | 0.89 | MAPT (0.41) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28821048 | 0.83 | GAA (0.34) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27224726 | 0.83 | KDM4C (0.41) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24849643 | 0.80 | NUDT1 (0.33) | — | |
| SCHEMBL30135702 | 0.80 | CYP1A2 (0.39) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL31401592 | 0.80 | MAPT (0.44) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL38651248 | 0.80 | MAPT (0.44) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31401688 | 0.78 | CYP1A2 (0.44) | MAPTKDM4CCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725941-A1 | ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-04-15 | — | — | EP | disclosed |
| CN-115803024-B | Compositions comprising aryl amide derivatives | 中外制药株式会社 | 2025-01-10 | — | — | CN | disclosed |
| CN-114929669-B | Aryl amide derivatives with antitumor activity | 中外制药株式会社 | 2024-11-29 | — | — | CN | disclosed |