Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 20/20 | 0.57 |
| ▸ | PLK3 | Q9H4B4 | 9/20 | 0.51 |
| ▸ | PLK2 | Q9NYY3 | 9/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25334099 | 0.90 | PLK1 (0.63) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL25031421 | 0.89 | PLK1 (0.59) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL25031422 | 0.86 | PLK1 (0.62) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL30135959 | 0.85 | PLK1 (0.54) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL30135899 | 0.83 | PLK1 (0.50) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL25031487 | 0.83 | PLK1 (0.52) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL1675947 | 0.83 | PLK1 (0.80) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL30136049 | 0.83 | PLK1 (0.48) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL25334301 | 0.83 | PLK1 (0.53) | PLK1PLK3PLK2BRD4BRDT | |
| SCHEMBL30135711 | 0.81 | PLK1 (0.71) | PLK1PLK3PLK2BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157850-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2023-04-05 | — | — | EP | disclosed |
| WO-2023018236-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |