SCHEMBL30136033

SCHEMBL30136033

O=C(c1cccc(O)c1)c1cccc(Br)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.61
CLK1 P49759 1/20 0.59
DYRK1A Q13627 1/20 0.59
DYRK1B Q9Y463 1/20 0.59
PARP1 P09874 2/20 0.57
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA6 P23280 1/20 0.55
CA9 Q16790 1/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 1/20 0.55
KDM4E B2RXH2 1/20 0.55
EGLN2 Q96KS0 1/20 0.55
CTSL P07711 3/20 0.52
HSD17B1 P14061 2/20 0.50
HSD17B2 P37059 2/20 0.50
AKR1C4 P17516 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18529814 1.00 FASN (0.61) FASNCLK1DYRK1ADYRK1BPARP1
SCHEMBL18529829 0.90 CTSL (0.58) FASNCLK1DYRK1ADYRK1BPARP1
SCHEMBL241785 0.89 PARP1 (0.68) PARP1NPC1RAB9ACTSLMEN1
SCHEMBL30153175 0.89 PARP1 (0.68) PARP1NPC1RAB9ACTSLMEN1
SCHEMBL4511367 0.88 PARP1 (0.57) FASNPARP1CA12CA1CA2
Hydrochloric Acid SCHEMBL27869733 0.87 PARP1 (0.65) PARP1NPC1RAB9ACTSLMEN1
SCHEMBL29699163 0.87 FASN (0.76) FASNCLK1DYRK1ADYRK1BPARP1
SCHEMBL809540 0.87 FASN (0.76) FASNCLK1DYRK1ADYRK1BPARP1
SCHEMBL26988699 0.86 CLK1 (0.62) FASNCLK1DYRK1ADYRK1BPARP1
SCHEMBL11290390 0.86 MAPT (0.58) CLK1DYRK1ADYRK1BPARP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701422-B Preparation method of KGP94 中国科学院昆明植物研究所 2024-02-09 CN claimed
CN-115701422-A Preparation method of KGP94 中国科学院昆明植物研究所 2023-02-10 CN claimed
CN-115701422-B Preparation method of KGP94 中国科学院昆明植物研究所 2024-02-09 CN disclosed
CN-115701422-A Preparation method of KGP94 中国科学院昆明植物研究所 2023-02-10 CN disclosed