Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CETP | P11597 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607788 | 1.00 | MAPT (0.62) | MAPTCETPHDAC3HDAC1HDAC2 | |
| SCHEMBL1817247 | 0.85 | POLB (0.61) | MAPTPOLBRXFP1MEN1KMT2A | |
| SCHEMBL15529987 | 0.85 | RXFP1 (0.60) | POLBRXFP1HPGD | |
| SCHEMBL28256535 | 0.84 | CETP (0.77) | CETPHDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL28258088 | 0.84 | CETP (0.77) | CETPHDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL12323604 | 0.84 | CETP (0.77) | CETPHDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL1816200 | 0.83 | POLB (0.58) | MAPTPOLBMEN1KMT2ACYP1A2 | |
| SCHEMBL27562556 | 0.82 | MEN1 (0.70) | MAPTMEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL5182843 | 0.82 | POLB (0.74) | MAPTPOLBMEN1KMT2ACYP1A2 | |
| SCHEMBL7111160 | 0.80 | KMT2A (0.47) | MAPTCETPHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113445066-B | Method for electrochemically synthesizing ortho-trifluoromethyl substituted aniline by using continuous flow | 南京先进生物材料与过程装备研究院有限公司 | 2022-12-20 | — | — | CN | disclosed |