SCHEMBL301366

SCHEMBL301366

Cn1c(N)nc(N)c(N)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
CLK4 Q9HAZ1 2/20 0.35
NTRK1 P04629 1/20 0.35
LTK P29376 1/20 0.35
TYRO3 Q06418 1/20 0.35
NTRK2 Q16620 1/20 0.35
TSHR P16473 1/20 0.34
PDE5A O76074 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
DAPK3 O43293 1/20 0.33
CSNK1A1 P48729 1/20 0.33
LIMK1 P53667 1/20 0.33
TNK2 Q07912 1/20 0.33
ROCK1 Q13464 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11679077 0.74 CSNK2A2 (0.35) KDM4EKMT2A
SCHEMBL9300537 0.74 DPP4 (0.32) KDM4EMEN1KMT2A
SCHEMBL8720564 0.74 RXFP1 (0.44) KDM4ETSHRMEN1KMT2A
SCHEMBL11679365 0.74 KDM4E (0.41) KDM4ECLK4NTRK1LTKTYRO3
SCHEMBL5157951 0.69
SCHEMBL11680197 0.67 KDM4E (0.37) KDM4ECLK4NTRK1LTKTYRO3
SCHEMBL11679843 0.67 ALDH1A1 (0.36) KDM4ETSHRMEN1KMT2A
SCHEMBL12235155 0.63 KDM4E (0.38) KDM4ECLK4NTRK1LTKTYRO3
SCHEMBL8986856 0.63 KDM4E (1.00) KDM4EMEN1KMT2A
SCHEMBL546237 0.63 KDM4E (0.42) KDM4ECLK4NTRK1LTKTYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120037794-A Preparation method and application of solvent-resistant polyamide composite membrane 南京工业大学 2025-05-27 CN claimed
US-20260074224-A1 SUPRAMOLECULE AND RECHARGEABLE LITHIUM BATTERIES INCLUDING THE SAME SAMSUNG SDI CO LTD (KR) 2026-03-12 US disclosed
CN-120037794-A Preparation method and application of solvent-resistant polyamide composite membrane 南京工业大学 2025-05-27 CN disclosed
EP-2405513-A1 BINDER COMPOSITION FOR ELECTRODES AND ELECTRODE MIX SLURRY I.S.T. Corporation (JP) 2012-01-11 EP disclosed
US-20110309293-A1 BINDER COMPOSITION FOR ELECTRODES AND ELECTRODE MIX SLURRY I.S.T. CORPORATION (JP) 2011-12-22 US disclosed
US-4043750-A OXIDATION HENKEL & CIE GMBH (DT) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260074224-A1 SUPRAMOLECULE AND RECHARGEABLE LITHIUM BATTERIES INCLUDING THE SAME NLRP1, ILK, S100A9 KDM4E 624/4885CLK4 111/4885NTRK1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.