SCHEMBL30136600

SCHEMBL30136600

Cc1c(C(N)C(F)(F)F)oc2cccc(F)c12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.32
KDM1A O60341 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24756036 0.79
SCHEMBL24756588 0.79 AR (0.33) AR
SCHEMBL24757829 0.78 CA2 (0.37)
SCHEMBL30136601 0.77 RAB9A (0.37)
SCHEMBL720359 0.73 KDM4E (0.34) ARKDM1A
SCHEMBL24755703 0.71 RAB9A (0.37) AR
SCHEMBL30136827 0.71 RAB9A (0.37) AR
SCHEMBL24756074 0.71 RAB9A (0.37) AR
SCHEMBL30136641 0.71 RAB9A (0.37) AR
SCHEMBL24324278 0.70 AR (0.40) ARKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4334298-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER Scorpion Therapeutics, Inc. (US) 2024-03-13 EP disclosed
WO-2022265993-A1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS, INC. (US) 2022-12-22 WO disclosed