Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687135 | 1.00 | POLB (0.45) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL28712277 | 1.00 | POLB (0.45) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL28694366 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL28705506 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9208976 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL336792 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9205224 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9727986 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL337168 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL5391201 | 0.87 | POLB (0.48) | POLBALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490625-A | Synthesis and refining method of meropenem side chain | 山东鑫泉医药有限公司 | 2022-12-20 | — | — | CN | disclosed |