Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208976 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9205224 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9727986 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL337168 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9200520 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9202856 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9728345 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL28694366 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9687135 | 0.89 | POLB (0.45) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL28712277 | 0.89 | POLB (0.45) | ALDH1A1MAPTHPGDTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012160576-A2 | A PROCESS FOR PREPARATION OF MEROPENEM | SEQUENT ANTI BIOTICS PRIVATE LIMITED (IN) | 2012-11-29 | — | — | WO | claimed |
| JP-3041066-A | — | — | None | — | — | JP | disclosed |
| EP-3430013-B1 | CARBAPENEM COMPOUNDS | ORCHID PHARMA LTD (IN) | 2023-11-15 | — | — | EP | disclosed |
| CN-109415365-B | Carbapenem compounds | 幽兰医药有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114163371-A | Meropenem side chain optical isomer, preparation method and application thereof, and detection method of impurities in Meropenem side chain | 天津市敬业精细化工有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111039945-B | Purification method for protecting meropenem | 山东安弘制药有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-111039945-A | Purification method for protecting meropenem | 山东安弘制药有限公司 | 2020-04-21 | — | — | CN | disclosed |
| US-9233963-B2 | Method for preparing meropenem using zinc powder | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-01-12 | — | — | US | disclosed |
| US-9233963-B2 | Method for preparing meropenem using zinc powder | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-01-12 | — | — | US | disclosed |
| US-9233963-B2 | Method for preparing meropenem using zinc powder | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-01-12 | — | — | US | disclosed |
| US-5424422-A | Beta-lactams and their production | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5310897-A | Beta-lactams and their production | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| JP-H0341066-A | 2-SUBSTITUTED AMINOCARBONYL-4-MERCAPTOPYRROLIDINE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 1991-02-21 | — | — | JP | disclosed |
| EP-0188816-B1 | NOVEL BETA-LACTAMS AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-10-17 | — | — | EP | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0188816-A1 | Novel beta-lactams and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |