Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053802 | 0.79 | CNR2 (0.45) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL25027294 | 0.79 | CNR2 (0.45) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL25024820 | 0.77 | CNR2 (0.47) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL3445946 | 0.75 | SCN9A (0.52) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL30137493 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL24119880 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1GAALMNATP53 | |
| SCHEMBL25026436 | 0.72 | ALOX5AP (0.57) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL4242830 | 0.72 | CYP2A13 (0.56) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL15915825 | 0.72 | CYP2A13 (0.56) | L3MBTL1POLBALDH1A1HIF1AEPAS1 | |
| SCHEMBL1977685 | 0.72 | CYP2A13 (0.51) | SMN1; SMN2L3MBTL1POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475567-A | Heterocyclic derivative, composition and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-08-09 | — | — | CN | disclosed |
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | disclosed |