SCHEMBL30138142

SCHEMBL30138142

Nc1ccc(C(=O)c2ccc(N)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
GAA P10253 1/20 0.47
POLB P06746 2/20 0.45
MAPK14 Q16539 3/20 0.45
MAPK13 O15264 2/20 0.45
MAPK12 P53778 2/20 0.45
MAPK11 Q15759 2/20 0.45
CDC25B P30305 1/20 0.45
ATM Q13315 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ADORA1 P30542 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
KDM4E B2RXH2 1/20 0.40
SETD7 Q8WTS6 1/20 0.40
PRMT1 Q99873 1/20 0.40
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524266 1.00 MAPT (0.47) MAPTGAAPOLBMAPK14MAPK13
SCHEMBL7901398 0.92 MAPT (0.56) MAPTGAAPOLBMAPK14MAPK13
SCHEMBL28105407 0.86 CES2 (0.42) MAPTGAAPOLBMEN1KMT2A
SCHEMBL2946213 0.83 KMT2A (0.47) MAPTGAAPOLBCDC25BATM
SCHEMBL7511521 0.81 MAPK14 (0.46) MAPTGAAPOLBMAPK14MAPK13
SCHEMBL27637318 0.79 MAPT (0.53) MAPTGAAPOLBMAPK14MAPK13
SCHEMBL27985225 0.78 MAPT (0.67) MAPTGAAPOLBMAPK14MAPK13
SCHEMBL30398493 0.76 MAPK13 (0.56) MAPTGAAMAPK14MAPK13MAPK12
SCHEMBL8422568 0.75 CYP3A4 (0.54) MAPTGAAPOLBCDC25BATM
SCHEMBL31457340 0.75 MAPK13 (0.49) MAPTGAAPOLBMAPK14MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113403021-B Composition slurry, preparation method thereof and film 宜昌奥马电子材料有限公司 2023-02-14 CN disclosed