SCHEMBL7901398

SCHEMBL7901398

Nc1ccc(C(=O)c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
GAA P10253 2/20 0.56
POLB P06746 1/20 0.53
ADORA1 P30542 1/20 0.49
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
USP2 O75604 2/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
HSD17B10 Q99714 1/20 0.46
AKR1C3 P42330 1/20 0.46
MAPK14 Q16539 3/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
MAPK13 O15264 2/20 0.44
MAPK12 P53778 2/20 0.44
MAPK11 Q15759 2/20 0.44
CDC25B P30305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30138142 0.92 MAPT (0.47) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL7524266 0.92 MAPT (0.47) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL27637318 0.86 MAPT (0.53) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL27985225 0.86 MAPT (0.67) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL27514569 0.80 ALDH1A1 (0.56) MAPTGAAADORA1ALDH1A1MEN1
SCHEMBL28123259 0.80 MEN1 (0.53) MAPTGAAADORA1ALDH1A1LMNA
SCHEMBL4782239 0.80 CCNE2 (0.48) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL4592877 0.79 MAPT (0.53) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL934810 0.79 AKR1C3 (0.59) MAPTGAAPOLBADORA1ALDH1A1
SCHEMBL2784914 0.79 AKR1C3 (0.61) MAPTGAAADORA1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325554-A Manufacturing method, modified conjugated diene polymer, rubber composition and the tire of modified conjugated diene polymer 株式会社普利司通 2019-10-11 CN disclosed
CN-106715479-B Catalyst for polymerization of conjugated diene, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and composition containing same 宇部兴产株式会社 2019-07-23 CN disclosed
CN-106604935-B Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire 株式会社普利司通 2019-02-22 CN disclosed
CN-109153737-A The manufacturing method of terminal-modified conjugated diolefin polymer, rubber composition, rubber product and terminal-modified conjugated diolefin polymer 株式会社普利司通 2019-01-04 CN disclosed
CN-106604935-A Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire 株式会社普利司通 2017-04-26 CN disclosed
CN-104220510-B Rubber composition for tire tread THE YOKOHAMA RUBBER CO.,LTD. (JP) 2016-04-13 CN disclosed
CN-104302696-B Rubber composition for tire THE YOKOHAMA RUBBER CO.,LTD. (JP) 2016-01-20 CN disclosed
CN-104302696-A Rubber composition for tire YOKOHAMA RUBBER CO LTD 2015-01-21 CN disclosed
CN-103237841-B Rubber composition for tire treads YOKOHAMA RUBBER CO LTD 2014-12-24 CN disclosed
CN-104220510-A Rubber composition for tire tread YOKOHAMA RUBBER CO LTD 2014-12-17 CN disclosed
CN-103237842-A Rubber composition for tire tread YOKOHAMA RUBBER CO LTD 2013-08-07 CN disclosed
CN-103221476-A Rubber composition for tire tread YOKOHAMA RUBBER CO LTD 2013-07-24 CN disclosed
CN-103102519-A Rubber composition, useful for tire tread of a pneumatic tire, comprises a diene based rubber containing end modifying groups, a conjugated diene based copolymer with modified ends, silica, soot and a silane coupling agent YOKOHAMA RUBBER CO LTD 2013-05-15 CN disclosed
CN-101906223-A The method of the butadiene polymer composition of preparation modification ASAHI CHEMICAL CORP (JP) 2010-12-08 CN disclosed
CN-100554285-C Modified conjugated diene copolymer, rubber combination and tire BRIDGESTONE CORP (JP) 2009-10-28 CN disclosed
CN-101370867-A Rubber composition containing modified polybutadiene rubber and tire BRIDGESTONE CORP (JP) 2009-02-18 CN disclosed
CN-101160328-A Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORP (JP) 2008-04-09 CN disclosed
CN-101155868-A Modified butadiene-based polymer composition ASAHI CHEMICAL CORP (JP) 2008-04-02 CN disclosed
US-6200718-B1 A POLYMERIZED TONER OF CORE-SHELL STRUCTURE, COMPRISING CORE PARTICLES COMPOSED OF COLORED POLYMER PARTICLES WHICH CONTAIN A COMPOUND HAVING >C=N+ STRUCTURE IN ITS MOLECULE AND A COLORANT AND A LAYER OF POLYMER COVERING CORE PARTICLES NIPPON ZEON CO., LTD. (JP) 2001-03-13 US disclosed
US-6146554-A FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES OPTISCHE WERKE G. RODENSTOCK (DE) 2000-11-14 US disclosed