SCHEMBL30138366

SCHEMBL30138366

Clc1ccc(COc2cccc(N3CCNCC3)n2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.54
HTR2A P28223 4/20 0.54
HTR2B P41595 3/20 0.54
HTR3A P46098 3/20 0.53
HTR1A P08908 2/20 0.53
CHRM4 P08173 1/20 0.53
ADRB1 P08588 1/20 0.53
CHRM5 P08912 1/20 0.53
CHRM1 P11229 1/20 0.53
CHRM3 P20309 1/20 0.53
FPR3 P25089 1/20 0.53
HTR1D P28221 1/20 0.53
HTR1B P28222 1/20 0.53
HTR1E P28566 1/20 0.53
GPR183 P32249 1/20 0.53
HTR7 P34969 1/20 0.53
HRH1 P35367 1/20 0.53
DRD3 P35462 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
GPR35 Q9HC97 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24918718 1.00 HTR2C (0.54) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL29664028 0.84 HTR2C (0.44) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL23363259 0.84 HTR2C (0.44) HTR2CHTR2AHTR2BHTR3AHTR1A
Hydrochloric Acid SCHEMBL31479953 0.83 HTR2C (0.45) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL30138390 0.81 PLD1 (0.56) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL23384872 0.81 PLD1 (0.56) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL23385197 0.80 HTR2C (0.53) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL24147522 0.78 HTR2A (0.53) HTR2CHTR2AHTR2BHTR3AHTR1A
SCHEMBL29668697 0.78 HTR2A (0.53) HTR2CHTR2AHTR2BHTR3AHTR1A
Hydrochloric Acid SCHEMBL25385019 0.77 HTR3A (0.54) HTR2CHTR2AHTR2BHTR3AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11932618-B2 GLP-1 receptor agonist and use thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2024-03-19 US disclosed
US-20230212140-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-07-06 US disclosed
US-11643403-B2 GLP-1 receptor agonist and use thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-05-09 US disclosed
US-20230013143-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230013143-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF GLP1R, GIPR, GPR119 HTR2C 493/4885HTR2A 459/4885HTR2B 407/4885
US-20230212140-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF GLP1R, GIPR, GPR119 HTR2C 493/4885HTR2A 459/4885HTR2B 407/4885
US-11643403-B2 GLP-1 receptor agonist and use thereof GLP1R, GIPR, GPR119 HTR2C 493/4885HTR2A 459/4885HTR2B 407/4885
US-11932618-B2 GLP-1 receptor agonist and use thereof GLP1R, GIPR, GPR119 HTR2C 493/4885HTR2A 459/4885HTR2B 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.