Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626178 | 1.00 | CAPN1 (0.43) | CAPN1OPRM1OPRD1RENACE | |
| SCHEMBL30139005 | 0.96 | REN (0.44) | OPRM1OPRD1RENACEKDM4E | |
| SCHEMBL30138988 | 0.93 | REN (0.45) | CAPN1RENACEKDM4EF2 | |
| SCHEMBL30139048 | 0.93 | REN (0.45) | CAPN1RENACEKDM4EF2 | |
| SCHEMBL30626180 | 0.91 | OPRM1 (0.51) | CAPN1OPRM1OPRD1BDKRB2CTSB | |
| SCHEMBL29397180 | 0.91 | OPRM1 (0.51) | CAPN1OPRM1OPRD1BDKRB2CTSB | |
| SCHEMBL31752434 | 0.91 | CAPN1 (0.48) | CAPN1OPRM1OPRD1BDKRB2CTSB | |
| SCHEMBL29760883 | 0.89 | CAPN1 (0.55) | CAPN1OPRM1OPRD1BDKRB2CTSB | |
| SCHEMBL30139064 | 0.89 | REN (0.48) | RENACEKDM4EF2LMNA | |
| SCHEMBL16468892 | 0.88 | CAPN1 (0.40) | CAPN1OPRM1OPRD1BDKRB2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162146-B | GIP-GLP-1 double-agonist compound | 成都奥达生物科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-115181173-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-14 | — | — | CN | claimed |