SCHEMBL30139043

SCHEMBL30139043

C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 4/20 0.39
▸ ACE P12821 9/20 0.39
▸ OPRM1 P35372 1/20 0.39
▸ OPRD1 P41143 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ F2 P00734 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ LTA4H P09960 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ PEPD P12955 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ HTR2A P28223 1/20 0.38
▸ PTGS2 P35354 1/20 0.38
▸ HRH1 P35367 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ PMP22 Q01453 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ ACE2 Q9BYF1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396694 0.97 CAPN1 (0.41) RENACEOPRM1OPRD1
SCHEMBL31115696 0.97 CAPN1 (0.41) RENACEOPRM1OPRD1
SCHEMBL29376028 0.90 OPRM1 (0.43) RENOPRM1OPRD1
SCHEMBL29375930 0.90 OPRM1 (0.43) RENOPRM1OPRD1
SCHEMBL30211634 0.90 CAPN1 (0.43) RENACEOPRM1OPRD1
SCHEMBL31259075 0.89 CAPN1 (0.44) OPRM1OPRD1
SCHEMBL31195363 0.89 REN (0.43) RENACEKDM4EF2LMNA
SCHEMBL29757422 0.88 CAPN1 (0.51) OPRM1OPRD1
SCHEMBL31140016 0.87 CAPN1 (0.41) RENOPRM1OPRD1
SCHEMBL30013216 0.87 CAPN1 (0.41) RENOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181173-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2022-10-14 — — CN claimed
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
WO-2025264785-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
WO-2025069009-A1 ROCK2 INHIBITORS IN THE TREATMENT OF OBESITY GRAVITON BIOSCIENCE BV (NL) 2025-04-03 — — WO disclosed
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