Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | CASP1 | P29466 | 4/20 | 1.00 |
| ▸ | CASP7 | P55210 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL30139617 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL15676607 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL16237902 | 0.91 | KDM4E (0.83) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL15844041 | 0.91 | KDM4E (0.83) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL31031153 | 0.89 | KDM4E (0.80) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4649257 | 0.87 | KDM4E (0.77) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL25235022 | 0.86 | ABCB1 (0.79) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL30397364 | 0.86 | ABCB1 (0.79) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL31675757 | 0.86 | ABCB1 (1.00) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4650613 | 0.86 | ABCB1 (1.00) | KDM4ECYP3A4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558811-A | 2- (3,4- Dimethoxyphenyls) -4- oxo -4H- chromene -3- yl acetates crystal form, preparation method | 上海捌加壹医药科技有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-105669625-A | 2-substituted benzopyran-4-one compounds and application thereof | 中国人民解放军第二军医大学 | 2016-06-15 | — | — | CN | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-20250368629-A1 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | MAYO FOUND MEDICAL EDUCATION & RES (US) | 2025-12-04 | — | — | US | disclosed |
| EP-4536210-A2 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | Mayo Foundation for Medical Education and Research (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119365193-A | Flavonoid compounds and methods and materials for treating fibrotic disorders using flavonoid compounds | 梅约医学教育与研究基金会 | 2025-01-24 | — | — | CN | disclosed |
| WO-2023244619-A2 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-2999467-B1 | USE OF A COMBINATION OF TWO COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF BONE DISORDERS | INST NAT DE LA RECH AGRONOMIQUE INRA (FR) | 2020-01-08 | — | — | EP | disclosed |
| CN-108558811-A | 2- (3,4- Dimethoxyphenyls) -4- oxo -4H- chromene -3- yl acetates crystal form, preparation method | 上海捌加壹医药科技有限公司 | 2018-09-21 | — | — | CN | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| CN-105669625-A | 2-substituted benzopyran-4-one compounds and application thereof | 中国人民解放军第二军医大学 | 2016-06-15 | — | — | CN | disclosed |
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2013-01-03 | — | — | US | disclosed |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-06-04 | — | — | US | disclosed |
| WO-2008156654-A2 | CYTOSKELETON MODULATORS FOR TREATING METABOLIC DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368629-A1 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | FABP1, FN1, MMP1 | KDM4E 4084/4885CYP3A4 2318/4885MAPT 1434/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | KDM4E 2309/4885CYP3A4 3010/4885MAPT 4313/4885 |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PC, PCK2, CS | KDM4E 3739/4885CYP3A4 2876/4885MAPT 357/4885 |
| US-20130005666-A1 | REPORTER SYSTEM FOR HIGH THROUGHPUT SCREENING OF COMPOUNDS AND USES THEREOF | NFE2, NFE2L2, UBE2N | KDM4E 4210/4885CYP3A4 2576/4885MAPT 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.