Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140141 | 0.89 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL31377619 | 0.82 | GPR119 (0.48) | PIK3CDGPR119 | |
| SCHEMBL30639982 | 0.82 | GPR119 (0.48) | PIK3CDGPR119 | |
| SCHEMBL30140379 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30140061 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30140176 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17687796 | 0.81 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL17687793 | 0.81 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30126906 | 0.80 | HPGDS (0.44) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29686088 | 0.79 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |