Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140174 | 0.88 | GPR119 (0.51) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30140120 | 0.88 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL30140215 | 0.88 | GPR119 (0.52) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30140434 | 0.87 | GPR119 (0.47) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30140322 | 0.84 | EGFR (0.54) | EGFRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30140205 | 0.84 | ERBB2 (0.51) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30140301 | 0.83 | GPR119 (0.55) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23570650 | 0.82 | GPR119 (0.52) | EGFRGPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30140071 | 0.81 | EGFR (0.55) | EGFRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30140351 | 0.81 | EGFR (0.48) | EGFRGPR119PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |